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The University of Chicago

Campaign Initiatives

Computing and AI

Push the boundaries of artificial intelligence and machine learning, advancing scholarship across science, engineering, and the humanities to deepen knowledge and discovery in a new era of thinking.

Thinking with, about, and without machines 

What if the question isn’t what AI can do, but what humans choose to do with it? 

We’re answering that question in one of the most ambitious intellectual bets in the University’s history. UChicago faculty and students are thinking with machines—using AI to hunt undruggable cancer proteins and read ancient civilizations through digital archives no human could survey alone. They are thinking about machines—asking whether AI can genuinely create, and whether it is quietly redrawing the boundary between governments and the people they govern. And they are thinking without machines—insisting that human judgment and inquiry are not optional. 

When over 400 faculty responded to an open call for AI research ideas, they came from archaeology, astrophysics, chemistry, law, medicine, economics, the arts, and beyond—all to explore what intelligent inquiry means in the age of AI. They were doing what Chicago Minds have always done: following the question wherever it leads, even when it leads somewhere no discipline has mapped before.  

The work ahead will define how intelligent systems shape human life for generations.  

Numbers at a Glance

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Contact

Matt Leroux
773.834.8943
leroux@uchicago.edu